概述

  • 产品名称Anti-TTC19抗体
    参阅全部 TTC19 一抗
  • 描述
    兔多克隆抗体to TTC19
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide: GTGAERLRTR GAPARGHGVL PLLAALAWFS RPAATAEQPG EDASDEAEAE, corresponding to N terminal amino acids 37-86 of Mouse TTC19

  • 阳性对照
    • NIH3T3 lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab66622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay 1:62500.

WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Mitochondrial protein required for formation of the mitochondrial complex III (PubMed:21278747). May also be required for the abcission step in cytokinesis, possibly regulating the ESCRT-III complex via its interaction with CHMP4B (PubMed:20208530). However, the involvement in cytokinesis requires additional experimental evidence.
  • 疾病相关Mitochondrial complex III deficiency, nuclear 2
  • 序列相似性Belongs to the TTC19 family.
    Contains 5 TPR repeats.
  • 细胞定位Mitochondrion inner membrane. Cytoplasm > cytoskeleton > microtubule organizing center > centrosome. Midbody. According to some authors, localizes to the centrosome during all stages of the cell cycle and is recruited to the midbody during cytokinesis (PubMed:20208530). However, the midbody localization could not be confirmed by others.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2010204O13Rik antibody
    • FLJ20343 antibody
    • MGC138312 antibody
    • MGC19520 antibody
    • mitochondrial antibody
    • RIKEN cDNA 2810460C24 antibody
    • Tetratricopeptide repeat protein 19 antibody
    • TPR repeat protein 19 antibody
    • Ttc 19 antibody
    • TTC19 antibody
    • TTC19_HUMAN antibody
    see all

Anti-TTC19 antibody 图像

  • Anti-TTC19 antibody (ab66622) at 1.25 µg/ml + NIH3T3 lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 42 kDa
    Observed band size : 42 kDa

Anti-TTC19 antibody (ab66622)参考文献

ab66622 has not yet been referenced specifically in any publications.

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