Anti-TSPYL1抗体(ab95943)

概述

  • 产品名称Anti-TSPYL1抗体
    参阅全部 TSPYL1 一抗
  • 描述
    兔多克隆抗体to TSPYL1
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 - 213 of Human TSPYL1

  • 阳性对照
    • WB: MOLT4 and Raji cell lysates IF: HeLa cells IHC-P: NCIN87 Xenograft

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab95943 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 49 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

靶标

  • 组织特异性Expressed in testis, ovary, liver, spleen, brain, kidney, prostate, lung, liver, and heart.
  • 疾病相关Defects in TSPYL1 are the cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT) [MIM:608800]. SIDDT is an autosomal recessive disorder. Affected infants appear normal at birth, develop signs of visceroautonomic dysfunction early in life, and die before 12 months of age of abrupt cardiorespiratory arrest. Features included bradycardia, hypothermia, severe gastroesophageal reflux, laryngospasm, bronchospasm, and abnormal cardiorespiratory patterns during sleep. Genotypic males with SIDDT had fetal testicular dysgenesis and ambiguous genitalia, with findings such as intraabdominal testes, dysplastic testes, deficient fetal testosterone production, fusion and rugation of the gonadal sac, and partial development of the penile shaft. Female sexual development was normal. Affected infants had an unusual staccato cry, similar to the cry of a goat.
  • 序列相似性Belongs to the nucleosome assembly protein (NAP) family.
  • 细胞定位Nucleus > nucleolus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • SIDDT antibody
    • Testis specific like protein Y encoded antibody
    • Testis specific Y encoded like protein 1 antibody
    • Testis-specific Y-encoded-like protein 1 antibody
    • TSPY like antibody
    • TSPY like 1 antibody
    • TSPY like protein 1 antibody
    • TSPY-like protein 1 antibody
    • TSPYL antibody
    • TSPYL1 antibody
    • TSYL1_HUMAN antibody
    see all

Anti-TSPYL1 antibody 图像

  • All lanes : Anti-TSPYL1 antibody (ab95943) at 1/1000 dilution

    Lane 1 : MOLT4 whole cell lysate
    Lane 2 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 49 kDa
  • ab95943, at a 1/200 dilution, staining TSPYL1 in paraformaldehyde-fixed HeLa cells by Immunofluorescence analysis. Right image is merged with a DNA probe.
  • ab95943, at a 1/100 dilution, staining TSPYL1 in a paraffin-embedded NCIN87 Xenograft by Immunohistochemical analysis.

Anti-TSPYL1 antibody (ab95943)参考文献

ab95943 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Application Western blot
Loading amount 20 µg
Gel Running Conditions Reduced Denaturing
Sample Human Cell lysate - whole cell (HeLa)
Specification HeLa
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: RT°C
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提交于 Nov 11 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"