概述

  • 产品名称Anti-TSPYL1抗体
    参阅全部 TSPYL1 一抗
  • 描述
    小鼠单克隆抗体to TSPYL1
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment: MSGLDGVKRT TPLQTHSIII SDQVPSDQDA HQYLRLRDQS EATQVMAEPG EGGSETVALP PPPPSEEGGV PQDAAGRGGT PQIRVVGGRG HVAIKAGQEE , corresponding to amino acids 1-101 of Human TSPYL1 with a 26kDa enzyme tag.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab76440 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 组织特异性Expressed in testis, ovary, liver, spleen, brain, kidney, prostate, lung, liver, and heart.
    • 疾病相关Defects in TSPYL1 are the cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT) [MIM:608800]. SIDDT is an autosomal recessive disorder. Affected infants appear normal at birth, develop signs of visceroautonomic dysfunction early in life, and die before 12 months of age of abrupt cardiorespiratory arrest. Features included bradycardia, hypothermia, severe gastroesophageal reflux, laryngospasm, bronchospasm, and abnormal cardiorespiratory patterns during sleep. Genotypic males with SIDDT had fetal testicular dysgenesis and ambiguous genitalia, with findings such as intraabdominal testes, dysplastic testes, deficient fetal testosterone production, fusion and rugation of the gonadal sac, and partial development of the penile shaft. Female sexual development was normal. Affected infants had an unusual staccato cry, similar to the cry of a goat.
    • 序列相似性Belongs to the nucleosome assembly protein (NAP) family.
    • 细胞定位Nucleus > nucleolus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • SIDDT antibody
      • Testis specific like protein Y encoded antibody
      • Testis specific Y encoded like protein 1 antibody
      • Testis-specific Y-encoded-like protein 1 antibody
      • TSPY like antibody
      • TSPY like 1 antibody
      • TSPY like protein 1 antibody
      • TSPY-like protein 1 antibody
      • TSPYL antibody
      • TSPYL1 antibody
      • TSYL1_HUMAN antibody
      see all

    Anti-TSPYL1 antibody 图像

    • Anti-TSPYL1 antibody (ab76440) at 5 µg/ml + immunogen at 0.1 µg

      Secondary
      Goat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

      Predicted band size : 37 kDa
      Observed band size : 37 kDa

    Anti-TSPYL1 antibody (ab76440)参考文献

    ab76440 has not yet been referenced specifically in any publications.

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