概述

  • 产品名称Anti-TSPAN12抗体
    参阅全部 TSPAN12 一抗
  • 描述
    兔多克隆抗体to TSPAN12
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the C-terminal region of Human TSPAN12 (NP_036470.1).

  • 阳性对照
    • T47D cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab93179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 35 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性TSPAN12 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. It is a regulator of cell surface receptor signal transduction and plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. It acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. It also acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. It activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP) and activates MMP14/MT1-MMP-dependent cleavage activity.
    • 细胞定位Cell membrane; Multi-pass membrane protein.
    • 数据库链接
    • 别名
      • 9030619E17 antibody
      • AI426782 antibody
      • AI663988 antibody
      • AW111457 antibody
      • MGC109305 antibody
      • NET 2 antibody
      • NET2 antibody
      • OTTHUMP00000211224 antibody
      • Tetraspan NET 2 antibody
      • Tetraspanin 12 antibody
      • Tetraspanin12 antibody
      • TM4SF12 antibody
      • Transmembrane 4 superfamily member 12 antibody
      • TSPAN 12 antibody
      see all

    Anti-TSPAN12 antibody 图像

    • Anti-TSPAN12 antibody (ab93179) at 1/100 dilution + T47D cell line lysate at 35 µg

      Predicted band size : 35 kDa

    Anti-TSPAN12 antibody (ab93179)参考文献

    ab93179 has not yet been referenced specifically in any publications.

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