Anti-TSH抗体[TSH 220] (ab76759)

概述

  • 产品名称Anti-TSH抗体[TSH 220]
    参阅全部 TSH 一抗
  • 描述
    小鼠单克隆抗体[TSH 220] to TSH
  • 特异性ab76759 labels thyrotrophic cells of the pituitary and may be useful for research in the classification of pituitary adenocarcinomas and differential identification of primary and metastatic tumors of the pituitary.
  • 经测试应用适用于: IHC-P, IHC-Fr, ICCmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human TSH, beta subunit.

  • 表位not known
  • 阳性对照
    • Human Anterior pituitary tissue.

性能

应用

Our Abpromise guarantee covers the use of ab76759 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
IHC-Fr
ICC
  • 应用说明ICC: 1/50 - 1/100.
    Note: this antibody can be used also in cell smears.

    IHC-P: 1/50 - 1/100 using streptavidin-Biotin system or polymer system.
    Note: The intensity of staining can be enhanced by antigen retriever (boiling tissue in 10 mM citrate, pH 6.0 for 15-20 mins, followed by cooling at RT for 20 mins).

    IHC-Fr: 1/50 - 1/100 using streptavidin-Biotin system or polymer system.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Thyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
    • 细胞定位Secreted
    • 数据库链接
    • 别名
      • CG ALPHA antibody
      • CGA antibody
      • Chorionic gonadotropin alpha polypeptide antibody
      • FSHA antibody
      • Glycoprotein hormones alpha polypeptide antibody
      • GPHA1 antibody
      • Thyroid stimulating hormone beta subunit antibody
      • Thyrotropin beta subunit antibody
      • TSH beta antibody
      • TSHA antibody
      • TSHB antibody
      see all

    Anti-TSH antibody [TSH 220] (ab76759)参考文献

    ab76759 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab76759.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"