Anti-Trypsin抗体[2C4] (ab17263)

概述

  • 产品名称Anti-Trypsin抗体[2C4]
    参阅全部 Trypsin 一抗
  • 描述
    小鼠单克隆抗体[2C4] to Trypsin
  • 特异性This antibody is specific for human trypsin, trypsinogen and trypsin in complex with alpha 1 antitrypsin.
  • 经测试应用适用于: Sandwich ELISA, ELISA, WBmore details
  • 种属反应性
    与反应: Cow, Human
  • 免疫原

    Full length native protein purified from human pancreatic tissue.

性能

应用

Our Abpromise guarantee covers the use of ab17263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Sandwich ELISA Use at an assay dependent dilution. Can be used as a detection antibody in conjugation with ab17262.
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Detects a band of approximately 24 kDa.

靶标

  • 功能Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates.
  • 疾病相关Defects in PRSS1 are a cause of hereditary pancreatitis (HPC) [MIM:167800]; also known as chronic pancreatitis (CP). HPC is an autosomal dominant disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks.
  • 序列相似性Belongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
  • 翻译后修饰Occurs in a single-chain form and a two-chain form, produced by proteolytic cleavage after Arg-122.
  • 细胞定位Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alpha-trypsin chain 2 antibody
    • Anionic trypsinogen antibody
    • Beta trypsin antibody
    • Beta-trypsin antibody
    • Brain trypsinogen antibody
    • Cationic trypsinogen antibody
    • Digestive zymogen antibody
    • Mesotrypsin antibody
    • Mesotrypsinogen antibody
    • MGC111183 antibody
    • MGC120174 antibody
    • MGC120175 antibody
    • MGC149362 antibody
    • MTG antibody
    • Nonfunctional trypsin 1 antibody
    • Pancreatic trypsinogen III antibody
    • Protease serine 1 (trypsin 1) antibody
    • Protease Serine 1 antibody
    • Protease serine 2 (trypsin 2) antibody
    • Protease serine 2 antibody
    • Protease serine 2 preproprotein antibody
    • Protease serine 3 (mesotrypsin) antibody
    • Protease serine 3 antibody
    • Protease serine 4 (trypsin 4 brain) antibody
    • Prss1 antibody
    • PRSS2 antibody
    • PRSS3 antibody
    • PRSS4 antibody
    • Serine protease 1 antibody
    • Serine protease 2 antibody
    • Serine protease 3 antibody
    • Serine protease 4 antibody
    • T9 antibody
    • TRP1 antibody
    • TRY1 antibody
    • TRY1_HUMAN antibody
    • TRY2 antibody
    • TRY3 antibody
    • TRY4 antibody
    • TRY8 antibody
    • TRYP1 antibody
    • TRYP2 antibody
    • Trypsin 1 antibody
    • Trypsin 2 antibody
    • Trypsin 3 antibody
    • Trypsin I antibody
    • Trypsin II antibody
    • Trypsin III antibody
    • Trypsin IV antibody
    • Trypsinogen 1 antibody
    • Trypsinogen 2 antibody
    • Trypsinogen 4 antibody
    • Trypsinogen 5 antibody
    • Trypsinogen A antibody
    • Trypsinogen, anionic antibody
    • Trypsinogen, cationic antibody
    • Ttrypsinogen IV antibody
    see all

Anti-Trypsin antibody [2C4] 图像

  • All lanes : Anti-Trypsin antibody [2C4] (ab17263) at 5 µg/ml

    Lane 1 : Natural human Trypsin protein (ab78527) at 1 µg
    Lane 2 : Natural human Trypsin protein (ab78527) at 0.1 µg

    Secondary
    Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 20 minutes

Anti-Trypsin antibody [2C4] (ab17263)参考文献

ab17263 has not yet been referenced specifically in any publications.

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