概述

  • 产品名称Anti-TRPV5抗体
    参阅全部 TRPV5 一抗
  • 描述
    山羊多克隆抗体to TRPV5
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide:

    C-SHRGWEILRQNT

    , corresponding to amino acids 697-708 of Human TRPV5 (NP_062815.2).

  • 阳性对照
    • Human Pancreas lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab77351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/16000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 83 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
    • 组织特异性Expressed at high levels in kidney, small intestine and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum.
    • 序列相似性Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.
      Contains 5 ANK repeats.
    • 翻译后修饰Glycosylated.
    • 细胞定位Apical cell membrane. Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity). The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Calcium transport protein 2 antibody
      • Calcium transporter 2 antibody
      • CAT 2 antibody
      • CAT2 antibody
      • ECAC 1 antibody
      • ECaC antibody
      • ECaC1 antibody
      • Epithelial calcium channel 1 antibody
      • Osm 9 like TRP channel 3 antibody
      • Osm-9-like TRP channel 3 antibody
      • OTRPC 3 antibody
      • OTRPC3 antibody
      • Transient receptor potential cation channel subfamily V member 5 antibody
      • TRPV 5 antibody
      • TrpV5 antibody
      • TRPV5_HUMAN antibody
      see all

    Anti-TRPV5 antibody 图像

    • Anti-TRPV5 antibody (ab77351) at 1 µg/ml + Human pancreas lysate in RIPA buffer at 35 µg

      Predicted band size : 83 kDa
      Observed band size : 83 kDa

    Anti-TRPV5 antibody (ab77351)参考文献

    ab77351 has not yet been referenced specifically in any publications.

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