概述

  • 产品名称
    Anti-TRPM6抗体
  • 描述
    豚鼠多克隆抗体to TRPM6
  • 经测试应用
    适用于: IHC-Frmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide:

    GCERDKNRSSLERHTRL

性能

应用

Our Abpromise guarantee covers the use of ab47017 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr 1/100 - 1/1000.

靶标

  • 相关性
    TRPM6 is an essential ion channel and serine/threonine-protein kinase, and is crucial for magnesium homeostasis. TRPM6 also has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. The various isoforms of the type M6-kinase lack the ion channel region.
  • 细胞定位
    Multi-pass membrane protein.
  • 数据库链接
  • 别名
    • CHAK2 antibody
    • Channel kinase 2 antibody
    • HMGX antibody
    • HOMG antibody
    • HSH antibody
    • Melastatin related TRP cation channel 6 antibody
    • Transient receptor potential cation channel subfamily M member 6 antibody
    see all

图片

  • Immunohistochemical staining of frozen rat kidney tissue, using ab47017. Secondary staining was carried out using a Cy3 conjugated antibody.

文献

This product has been referenced in:
  • Boyden LM  et al. Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature 482:98-102 (2012). Read more (PubMed: 22266938) »
  • Sipos F  et al. Peripheral blood based discrimination of ulcerative colitis and Crohn's disease from non-IBD colitis by genome-wide gene expression profiling. Dis Markers 30:1-17 (2011). Read more (PubMed: 21508504) »

See all 2 Publications for this product

客户评价及客户问答

Thank you for your reply and your patience with this response.

I heard back from the lab in Australia, and unfortunately none of our anti-TRPM6 antibodies (ab47017, ab62990, ab63089, ab72153, ab74850, ab77499, ab79227) show significant homolo...

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Thank you for your inquiry.

I just wanted to give you an update.

We have 7 anti-TRPM6 antibodies in the catalogue. We wouldn't expect ab47017 to work in bovine, because the immunogen sequence really does not show any homology with b...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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