概述

  • 产品名称Anti-TRPC4AP抗体
    参阅全部 TRPC4AP 一抗
  • 描述
    山羊多克隆抗体to TRPC4AP
  • 特异性This antibody is expected to recognize both reported TRPC4AP isoforms (NP_955400.1; NP_056453.1).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide: C-

    KLTQETTYPNTYIFD

    , corresponding to internal sequence amino acids 118-132 of Human TRPC4AP (NP_056453.1; NP_955400.1).

  • 阳性对照
    • U937 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab90431 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 91 kDa).

靶标

  • 功能Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
  • 通路Protein modification; protein ubiquitination.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C20orf188 antibody
    • TRPC4AP antibody
    • Chromosome 20 open reading frame 188 antibody
    • Protein TAP1 antibody
    • Protein TRUSS antibody
    • Short transient receptor potential channel 4 associated protein antibody
    • Short transient receptor potential channel 4-associated protein antibody
    • TAP1 protein antibody
    • TNF receptor ubiquitous scaffolding/signaling protein antibody
    • TNF-receptor ubiquitous scaffolding/signaling protein antibody
    • TP4AP_HUMAN antibody
    • Transient receptor potential cation channel, subfamily C, member 4 associated protein antibody
    • Trp4 associated protein antibody
    • Trp4-associated protein antibody
    • Trpc4 associated protein antibody
    • Trpc4-associated protein antibody
    • TRPC4AP antibody
    • TRRP4AP antibody
    • TRUSS antibody
    • Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein antibody
    see all

Anti-TRPC4AP antibody 图像

Anti-TRPC4AP antibody (ab90431)参考文献

ab90431 has not yet been referenced specifically in any publications.

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