Anti-Troponin I fast + slow skeletal muscle抗体[12F10] (ab110132)

概述

  • 产品名称Anti-Troponin I fast + slow skeletal muscle抗体[12F10]
    参阅全部 Troponin I fast + slow skeletal muscle 一抗
  • 描述
    小鼠单克隆抗体[12F10] to Troponin I fast + slow skeletal muscle
  • 特异性Cross-reactivity with Cardiac Troponin I is less than 0.05%.
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Human
  • 免疫原

    Mouse Troponin I fast + slow skeletal muscle.

  • 阳性对照
    • Human skeletal muscle tissue.

性能

应用

Our Abpromise guarantee covers the use of ab110132 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 21 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 相关性Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue.
  • 细胞定位Cytoplasmic and Nuclear
  • 数据库链接
  • 别名
    • AMCD2B antibody
    • DA2B antibody
    • DKFZp451O223 antibody
    • Fast twitch skeletal muscle troponin I antibody
    • FSSV antibody
    • fsTnI antibody
    • OTTHUMP00000014141 antibody
    • OTTHUMP00000014142 antibody
    • OTTHUMP00000014143 antibody
    • OTTHUMP00000033877 antibody
    • OTTHUMP00000033909 antibody
    • OTTHUMP00000033910 antibody
    • SSTNI antibody
    • TNN1 antibody
    • Troponin I fast twitch 2 antibody
    • Troponin I type 1 (skeletal, slow) antibody
    • Troponin I type 2 (skeletal, fast) antibody
    • Troponin I, fast skeletal muscle antibody
    • Troponin I, fast twitch isoform antibody
    • Troponin I, fast twitch skeletal muscle isoform antibody
    • Troponin I, skeletal, fast antibody
    • Troponin I, slow skeletal muscle antibody
    • Troponin I, slow twitch isoform antibody
    see all

Anti-Troponin I fast + slow skeletal muscle antibody [12F10] 图像

  • ab110132 at 10 µg/ml staining Troponin I fast + slow skeletal muscle in Formalin-Fixed, Paraffin-Embedded Human skeletal muscle tissue by Immunohistochemistry. Detection utilised biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Anti-Troponin I fast + slow skeletal muscle antibody [12F10] (ab110132)参考文献

ab110132 has not yet been referenced specifically in any publications.

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