Anti-Tropomodulin 2抗体(ab67407)
Key features and details
- Mouse polyclonal to Tropomodulin 2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Tropomodulin 2抗体
参阅全部 Tropomodulin 2 一抗 -
描述
小鼠多克隆抗体to Tropomodulin 2 -
宿主
Mouse -
特异性
ab67407 is reactive against mammalian transfected lysate -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human Tropomodulin 2 aa 1-400. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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阳性对照
- ICC: Murine Neuroblastoma (N1E-115) cells. WB: Tropomodulin 2 transfected 293T lysate, N1E-115 mouse neuroblastoma.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.4
Constituent: PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab67407于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (2) |
1/500 - 1/1000. Detects a band of approximately 39.6 kDa.
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说明 |
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WB
1/500 - 1/1000. Detects a band of approximately 39.6 kDa. |
靶标
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相关性
Tropomodulin is the actin-capping protein for the slow growing end of filamentous actin. Tropomodulin 2 is a neuronal specific isoform which is the major binding protein to brain tropomyosin in rat. -
细胞定位
Cytoplasm; cytoskeleton -
数据库链接
- Entrez Gene: 29767 Human
- Omim: 602928 Human
- SwissProt: Q9NZR1 Human
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别名
- Tropomodulin 2 antibody
- MGC39481 antibody
- N Tmod antibody
see all
图片
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All lanes : Anti-Tropomodulin 2 antibody (ab67407) at 1/500 dilution
Lane 1 : Tropomodulin 2 transfected 293T lysate
Lane 2 : Non transfected 293T lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Observed band size: 39.6 kDa why is the actual band size different from the predicted? -
Lane 1 : Anti-Tropomodulin 2 antibody (ab67407) at 1/1000 dilution
Lane 2 : Anti-Tropomodulin 2 antibody [EPR6353] (ab124833) at 1/1000 dilution
All lanes : N1E-115 mouse neuroblastoma
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Polyclonal HRP conjugate at 1/5000 dilution
数据表及文件
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Datasheet download
文献 (4)
ab67407 被引用在 4 文献中.
- Omotade OF et al. Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation. J Neurosci 38:10271-10285 (2018). PubMed: 30301754
- Gu QH et al. miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement. Nat Commun 6:6789 (2015). PubMed: 25858512
- Hu Z et al. miR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression. Nat Commun 5:3263 (2014). WB, ICC/IF . PubMed: 24535612
- Sun Y et al. A gel-based proteomic method reveals several protein pathway abnormalities in fetal Down syndrome brain. J Proteomics 74:547-57 (2011). WB ; Human . PubMed: 21262400