概述

  • 产品名称
  • 描述
    山羊多克隆抗体to TROP2
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Cow, Dog, Pig, Chimpanzee, Rhesus monkey
  • 免疫原

    Synthetic peptide corresponding to Human TROP2 aa 195-208 (internal sequence).
    Sequence:

    C-HYEQPTIQIELRQN


    Database link: NP_002344.2

  • 阳性对照
    • WB: Human prostate lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab77551 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunising peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab77551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.

Peptide ELISA: Antibody detection limit dilution 1/4000. 

WB Use a concentration of 0.2 - 0.5 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

靶标

  • 功能
    May function as a growth factor receptor.
  • 组织特异性
    Placenta, pancreatic carcinoma cell lines.
  • 疾病相关
    Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) [MIM:204870]; also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.
  • 序列相似性
    Belongs to the EPCAM family.
    Contains 1 thyroglobulin type-1 domain.
  • 翻译后修饰
    The N-terminus is blocked.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cell surface glycoprotein Trop 2 antibody
    • Cell surface glycoprotein Trop-2 antibody
    • Cell surface glycoprotein Trop2 antibody
    • Epithelial glycoprotein 1 antibody
    • GA733 1 antibody
    • GA7331 antibody
    • M1S 1 antibody
    • M1S1 antibody
    • Membrane component chromosome 1 surface marker 1 antibody
    • Pancreatic carcinoma marker protein GA733 1 antibody
    • Pancreatic carcinoma marker protein GA733-1 antibody
    • Pancreatic carcinoma marker protein GA7331 antibody
    • TACD 2 antibody
    • TACD2_HUMAN antibody
    • TACSTD 2 antibody
    • Tacstd2 antibody
    • Trop 2 antibody
    • Trop2 antibody
    • Tumor associated calcium signal transducer 2 precursor antibody
    • Tumor-associated calcium signal transducer 2 antibody
    see all

Anti-TROP2 antibody 图像

  • Anti-TROP2 antibody (ab77551) at 0.2 µg/ml + Human Prostate lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 37 kDa
    Observed band size : 37 kDa
    Primary incubation was 1 hour.

实验方案

Anti-TROP2 antibody (ab77551)参考文献

ab77551 has not yet been referenced specifically in any publications.

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