Anti-TrkC抗体(ab33656)

概述

  • 产品名称Anti-TrkC抗体
    参阅全部 TrkC 一抗
  • 描述
    山羊多克隆抗体to TrkC
  • 特异性This antibody is specific for rat TrkC at 145kDa and an additional band at approximately 100kDa.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Chicken, Pig
  • 免疫原

    Recombinant entire extracellular domain of rat TrkC receptor, corresponding to aa1-429, expressed in COS cells.

  • 阳性对照
    • Mouse brain membrane protein preparation.

性能

应用

Our Abpromise guarantee covers the use of ab33656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 145 kDa (predicted molecular weight: 68 kDa).

靶标

  • 功能Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties.
  • 组织特异性Widely expressed but mainly in nervous tissue. Isoform B is expressed at higher levels in adult brain than in fetal brain.
  • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 2 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Ligand-mediated auto-phosphorylation.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 2.7.10.1 antibody
    • ETS related protein neurotrophic receptor tyrosine kinase fusion antibody
    • ETS related protein neurotrophic receptor tyrosine kinase fusion protein antibody
    • ETV6 NTRK3 fusion antibody
    • GP145 TrkC antibody
    • gp145(trkC) antibody
    • GP145-TrkC antibody
    • GP145TrkC antibody
    • Neurotrophic tyrosine kinase receptor type 3 antibody
    • Neurotrophin 3 receptor antibody
    • NT 3 growth factor receptor antibody
    • NT 3 growth factor receptor precursor antibody
    • NT 3 receptor antibody
    • NT-3 growth factor receptor antibody
    • Ntrk3 antibody
    • NTRK3_HUMAN antibody
    • OTTHUMP00000192915 antibody
    • TRK C antibody
    • Trk-C antibody
    • TRKC antibody
    • TrkC tyrosine kinase antibody
    • Tyrosine kinase receptor C antibody
    see all

Anti-TrkC antibody (ab33656)参考文献

ab33656 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. The immunogen for this product comprises the entire extracellular domain of rat TrkC receptor, corresponding to 1-429a.a, expressed in COS cells. Three isoforms of TrkC (isoforms A, B and C) differ in their amino aci...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"