Mouse, Rat, Horse, Cow, Cat, Pig
Synthetic peptide corresponding to a region within internal sequence amino acids 396-445 (IRLRKGNEYR AGTDEYPILS LPVPPRRVGI FVDYEAHDIS FYNVTDCGSH) of human TRIM68 (NP_060543).
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
Concentration information loading...
Immunogen affinity purified
Purified by peptide affinity chromatography method.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 5 µg/ml.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Functions as an ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.
Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells.
Protein modification; protein ubiquitination.
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.
The RING domain is essential for ubiquitin E3 ligase activity.
Cytoplasm > perinuclear region. Nucleus. Colocalized with AR in nucleus.
Information by UniProt
- E3 ubiquitin-protein ligase TRIM68 antibody
- FLJ10369 antibody
- GC109 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"