参阅全部 TRIM68 一抗
Recombinant fragment: KQSIVWEFEK YQRLLEKKQP PHRQLGAEVA AALASLQREA AETMQKLELN HSELIQQSQV LWRMIAELKE RSQRPVRWML QDIQEVLNRS KSWSLQQPEP , corresponding to amino acids 181-281 of Human TRIM68
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- 存储溶液Preservative: None
PBS, pH 7.2
Concentration information loading...
- 纯度Protein G purified
应用说明WB: Use at a concentration of 1-5 µg/ml.
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- 功能Functions as an ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.
- 组织特异性Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells.
- 通路Protein modification; protein ubiquitination.
- 序列相似性Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.
- 结构域The RING domain is essential for ubiquitin E3 ligase activity.
- 细胞定位Cytoplasm > perinuclear region. Nucleus. Colocalized with AR in nucleus.
Information by UniProt
- E3 ubiquitin-protein ligase TRIM68 antibody
- FLJ10369 antibody
- GC109 antibody
Anti-TRIM68 antibody (ab57436)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"