Anti-TRIM41抗体(ab111580)
Key features and details
- Rabbit polyclonal to TRIM41
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TRIM41抗体
参阅全部 TRIM41 一抗 -
描述
兔多克隆抗体to TRIM41 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant fragment, corresponding to a region within amino acids 284-482 of Human TRIM41 (AAH90953).
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阳性对照
- HeLa whole cell lysate; HeLa cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111580于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 72 kDa.
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ICC/IF |
1/100 - 1/500.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 72 kDa. |
ICC/IF
1/100 - 1/500. |
靶标
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功能
Functions as an E3 ligase that catalyzes the ubiquitin-mediated degradation of protein kinase C. -
组织特异性
Expressed in multiple tissues with the highest levels in heart and skeletal muscle. -
通路
Protein modification; protein ubiquitination. -
序列相似性
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger. -
翻译后修饰
Auto-ubiquitinated. -
细胞定位
Cytoplasm. Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 90933 Human
- Entrez Gene: 211007 Mouse
- Entrez Gene: 303088 Rat
- Omim: 610530 Human
- SwissProt: Q8WV44 Human
- SwissProt: Q5NCC3 Mouse
- Unigene: 441488 Human
- Unigene: 794 Mouse
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别名
- E3 ubiquitin-protein ligase TRIM41 antibody
- MGC1127 antibody
- MGC31991 antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab111580 被引用在 1 文献中.
- Kato K et al. Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol Cell 81:599-613.e8 (2021). PubMed: 33373584