This antibody is expected to recognise both human isoforms.
Synthetic peptide: ERSPDVSPGPSRS, corresponding to N terminal amino acids 2-14 of Human TRIM35.
Principal Names – Likely ortholog of mouse macrophage-derived apoptosis-inducing RBCC (RING-B-box-coiled-coil) protein.
Official Gene Symbol - TRIM35.
GenBank Accession Number – NP_055881; NP_741983.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 5mg/ml Tris, pH 7.3
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Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 57 kDa).Can be blocked with Human TRIM35 peptide (ab23034).
May play a role as a tumor suppressor. Implicated in the cell death mechanism.
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.
The RING finger domain and the coiled-coil region are required for the apoptosis-inducing activity.
Cytoplasm. Nucleus. Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.
Information by UniProt
- 0710005M05Rik antibody
- A430106H13Rik antibody
- AW046487 antibody
Anti-TRIM35 antibody (ab4388)参考文献
has not yet been referenced specifically in any publications.
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