概述

  • 产品名称Anti-TRIM抗体[TRIM-04]
    参阅全部 TRIM 一抗
  • 描述
    小鼠单克隆抗体[TRIM-04] to TRIM
  • 特异性Human T cell receptor-interacting molecule (TRIM)
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 29-186 of Human TRIM.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 15mM Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度>95% by SDS-PAGE
  • 纯化说明Purified from ascites by protein-A affinity chromatography.
  • 克隆单克隆
  • 克隆编号TRIM-04
  • 同种型IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab9529 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
  • 应用说明IP: Use at an assay dependant concentration.
    WB: Use at an assay dependant concentration. Use under non-reducing conditions.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
    • 组织特异性Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).
    • 发展阶段Strongly expressed in fetal thymus at weeks 17-24 of gestation. Undetectable in bone marrow and fetal liver.
    • 翻译后修饰Phosphorylated on tyrosines by LCK or FYN upon TCR activation.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • HSPC062 antibody
      • pp29/30 antibody
      • T cell receptor interacting molecule antibody
      • T-cell receptor-associated transmembrane adapter 1 antibody
      • T-cell receptor-interacting molecule antibody
      • TCRIM antibody
      • TRAT1 antibody
      • TRAT1_HUMAN antibody
      • TRIM antibody
      see all

    Anti-TRIM antibody [TRIM-04] (ab9529)参考文献

    This product has been referenced in:
    • Sospedra M  et al. Redundancy in antigen-presenting function of the HLA-DR and -DQ molecules in the multiple sclerosis-associated HLA-DR2 haplotype. J Immunol 176:1951-61 (2006). WB ; Human . Read more (PubMed: 16424227) »
    • Kirchgessner H  et al. The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. J Exp Med 193:1269-84 (2001). Read more (PubMed: 11390434) »

    See all 3 Publications for this product

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    Merci de nous avoir contactés.

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    Read More

    This antibody reacts with the T cell receptor-interacting molecule (TRIM). I believe that this is a different protein to the protein you are interested in.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"