Trifluoperazine dihydrochloride (ab120739)

概述

  • 产品名称Trifluoperazine dihydrochloride
  • 描述
    Cell-permeable calmodulin antagonist
  • 生物学描述Cell-permeable calmodulin antagonist. Dopamine receptor antagonist. Stimulates ER Ca2+ ATPase activity at low concentrations and inhibits at higher concentrations. Antipsychotic.
  • 纯度> 99%

性能

    Trifluoperazine dihydrochloride (ab120739)参考文献

    This product has been referenced in:
    • Feldkamp MD  et al. Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulin. Proteins 78:2265-82 (2010). Read more (PubMed: 20544963) »
    • Khan SZ  et al. The effects of phenothiazines and other calmodulin antagonists on the sarcoplasmic and endoplasmic reticulum Ca(2+) pumps. Biochem Pharmacol 60:1797-806 (2000). Read more (PubMed: 11108794) »
    • Vandonselaar M  et al. Trifluoperazine-induced conformational change in Ca(2+)-calmodulin. Nat Struct Biol 1:795-801 (1994). Read more (PubMed: 7634090) »
    • Seeman P  et al. Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 261:717-9 (1976). Read more (PubMed: 945467) »

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    Thank you for your technical enquiry. After checking our records it
    appears that there is an inaccuracy on the datasheet. I would like to
    confirm that ab120739 is an antagonist of calmodulin.
    I would like to apologize for this inacc...

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