Anti-Trichosantin抗体[TCST1] (ab63246)

概述

  • 产品名称Anti-Trichosantin抗体[TCST1]
  • 描述
    小鼠单克隆抗体[TCST1] to Trichosantin
  • 特异性ab63246 reacts with Trichosantin.
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein (purified)

性能

应用

Our Abpromise guarantee covers the use of ab63246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.

靶标

  • 相关性Trichosanthin, an abortifacient, immunosuppressive and anti-tumor protein purified from the traditional Chinese herb medicine Tian Hua Fen, is a potent inhibitor against HIV-1 replication. Under normal enzymatic digestion conditions, trichosanthin cleaves the supercoiled double-stranded DNA to produce nicked circular and linear DNA. Trichosanthin has no effect on linear double-stranded DNA. Neither does it convert relaxed circular duplex DNA into a supercoiled form in the presence of ATP. Thus trichosanthin is not a DNA gyrase. However, trichosanthin can cleave the relaxed circular DNA into a linear form, indicating that both the circular as well as the supercoiled forms are essential for trichosanthin recognition. In addition, trichosanthin contains one calcium metal ion per protein molecule, which presumably is related to its endonucleolytic activity.
  • 别名
    • EC 3.2.2.22 antibody
    • rRNA N-glycosidase antibody
    • TCS antibody
    • TCST antibody
    • trichosanthin antibody
    see all

Anti-Trichosantin antibody [TCST1] (ab63246)参考文献

ab63246 has not yet been referenced specifically in any publications.

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