概述

  • 产品名称Anti-TREX1抗体
    参阅全部 TREX1 一抗
  • 描述
    小鼠多克隆抗体to TREX1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-304 of Human TREX1

性能

应用

Our Abpromise guarantee covers the use of ab67192 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 39 kDa).
    Detection Antibody Pair.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性TREX1 is the major 3'->5' DNA exonuclease in human cells. The protein is a non processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A mediated cell death. Mutations in this gene result in Aicardi Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene.
    • 细胞定位Nuclear
    • 数据库链接
    • 别名
      • 3' 5' exonuclease TREX1 antibody
      • 3' repair exonuclease 1 antibody
      • AGS1 antibody
      • AGS5 antibody
      • CRV antibody
      • Deoxyribonuclease III, dnaQ/mutD (E. coli) like antibody
      • DKFZp434J0310 antibody
      • DNase III antibody
      • DRN3 antibody
      • HERNS antibody
      • Three prime repair exonuclease 1 antibody
      • TREX1 antibody
      see all

    Anti-TREX1 antibody 图像

    • All lanes : Anti-TREX1 antibody (ab67192) at 1/500 dilution

      Lane 1 : TREX1 transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 25 µg/ml per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 39 kDa
      Observed band size : 36 kDa (why is the actual band size different from the predicted?)

    Anti-TREX1 antibody (ab67192)参考文献

    This product has been referenced in:

    See 1 Publication for this product

    Product Wall

    Thank you for contacting us.
    I am sorry to hear that the antibodies don't seem to work as expected.

    As we discussed over the phone, the following protocols tips can help with improving your results:

    1) loading more protein onto th...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"