Anti-TREM1抗体[RM0138-3C66] (ab86490)

概述

  • 产品名称Anti-TREM1抗体[RM0138-3C66]
    参阅全部 TREM1 一抗
  • 描述
    大鼠单克隆抗体[RM0138-3C66] to TREM1
  • 特异性This antibody detects mouse of TREM1, but not TREM2b in Western blotting.
  • 经测试应用适用于: WB, IHC-Frmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse recombinant protein of the extracellular domain of TREM1

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明The IgG fraction of culture supernatant was purified by Protein A affinity chromatography.
  • 克隆单克隆
  • 克隆编号RM0138-3C66
  • 同种型IgG2
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab86490 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 26 kDa.
IHC-Fr 1/50 - 1/100.

靶标

  • 功能Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
  • 组织特异性Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes.
  • 序列相似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 翻译后修饰Glycosylated.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD354 antibody
    • OTTMUSP00000018206 antibody
    • TREM 1 antibody
    • TREM-1 antibody
    • TREM1 antibody
    • TREM1_HUMAN antibody
    • Triggering receptor expressed on monocytes 1 antibody
    • Triggering receptor expressed on myeloid cells 1 antibody
    • Triggering receptor TREM 1 antibody
    • Triggering receptor TREM1 antibody
    see all

Anti-TREM1 antibody [RM0138-3C66] (ab86490)参考文献

ab86490 has not yet been referenced specifically in any publications.

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Thank you very much for your email and your interest and collaboration offer. Thank you also for your patience while I was investigating. Please find here the answers to your questions: 1.) Those two antibodies are different clones. The ab86490 is lcon...

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