Anti-TREM1抗体[L5-B8] (ab106153)

概述

  • 产品名称Anti-TREM1抗体[L5-B8]
    参阅全部 TREM1 一抗
  • 描述
    大鼠单克隆抗体[L5-B8] to TREM1
  • 经测试应用适用于: WB, Functional Studies, Flow Cyt, ICC/IFmore details
    不适用于: IHC-Fr or IHC-P
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse TREM1-Human IgG-Fc fusion protein.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab106153 is 0.2 µm filtered.
  • 克隆单克隆
  • 克隆编号L5-B8
  • 同种型IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106153 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50. Predicted molecular weight: 26 kDa.
Functional Studies Use at an assay dependent concentration.
Flow Cyt 1/50. ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
ICC/IF Use at an assay dependent concentration.
  • 应用说明Is unsuitable for IHC-Fr or IHC-P.
  • 靶标

    • 功能Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
    • 组织特异性Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes.
    • 序列相似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 翻译后修饰Glycosylated.
    • 细胞定位Secreted and Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD354 antibody
      • OTTMUSP00000018206 antibody
      • TREM 1 antibody
      • TREM-1 antibody
      • TREM1 antibody
      • TREM1_HUMAN antibody
      • Triggering receptor expressed on monocytes 1 antibody
      • Triggering receptor expressed on myeloid cells 1 antibody
      • Triggering receptor TREM 1 antibody
      • Triggering receptor TREM1 antibody
      see all

    Anti-TREM1 antibody [L5-B8] 图像

    • ab106153 in flow cytometry. Goat ant-rat-PE (grey line) and ab106153/Goat anti-rat-PE (green line).

    Anti-TREM1 antibody [L5-B8] (ab106153)参考文献

    ab106153 has not yet been referenced specifically in any publications.

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