概述

  • 产品名称Anti-TREM1抗体
    参阅全部 TREM1 一抗
  • 描述
    小鼠单克隆抗体to TREM1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 21-235 of Human TREM1

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2b
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab57260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
    • 组织特异性Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes.
    • 序列相似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 翻译后修饰Glycosylated.
    • 细胞定位Secreted and Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD354 antibody
      • OTTMUSP00000018206 antibody
      • TREM 1 antibody
      • TREM-1 antibody
      • TREM1 antibody
      • TREM1_HUMAN antibody
      • Triggering receptor expressed on monocytes 1 antibody
      • Triggering receptor expressed on myeloid cells 1 antibody
      • Triggering receptor TREM 1 antibody
      • Triggering receptor TREM1 antibody
      see all

    Anti-TREM1 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57260 TREM1 antibody at 1ug/ml. Detected band size is around 50 kDa.

    Anti-TREM1 antibody (ab57260)参考文献

    ab57260 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"