Anti-Trefoil Factor 3抗体(ab57752)

概述

  • 产品名称Anti-Trefoil Factor 3抗体
    参阅全部 Trefoil Factor 3 一抗
  • 描述
    小鼠单克隆抗体to Trefoil Factor 3
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein: EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF, corresponding to amino acids 15-74 of Human Trefoil Factor 3

性能

应用

Our Abpromise guarantee covers the use of ab57752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
IHC-P Use a concentration of 3 µg/ml.

靶标

  • 功能Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
  • 组织特异性Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus.
  • 序列相似性Contains 1 P-type (trefoil) domain.
  • 细胞定位Secreted > extracellular space > extracellular matrix > apical lamina.
  • Information by UniProt
  • 数据库链接
  • 别名
    • hITF antibody
    • hP1.B antibody
    • Intestinal trefoil factor antibody
    • ITF antibody
    • mITF antibody
    • OTTMUSP00000021729 antibody
    • P1B antibody
    • Polypeptide P1.B antibody
    • TFF3 antibody
    • TFF3_HUMAN antibody
    • TFI antibody
    • TREFOIL antibody
    • Trefoil factor (intestinal) antibody
    • Trefoil factor 3 antibody
    see all

Anti-Trefoil Factor 3 antibody 图像

  • Trefoil Factor 3 antibody (ab57752) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.
  • Western blot against tagged recombinant protein immunogen using ab57752 Trefoil Factor 3 antibody at 1ug/ml. Predicted band size of immunogen is 33 kDa

Anti-Trefoil Factor 3 antibody (ab57752)参考文献

This product has been referenced in:
  • Ding A  et al. Impact of NPM, TFF3 and TACC1 on the prognosis of patients with primary gastric cancer. PLoS One 8:e82136 (2013). IHC-P ; Human . Read more (PubMed: 24358147) »
  • Iwasaki M  et al. Longitudinal cell formation in the entire human small intestine is correlated with the localization of Hath1 and Klf4. J Gastroenterol 46:191-202 (2011). IHC-P ; Human . Read more (PubMed: 21125297) »

See all 3 Publications for this product

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This kit will work with mouse IgM antiobodies as well.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Free Rabbit monoc...

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ab127055 kit can be used with any mouse antibody - this mean the kit would be suitable.

Please note ab49536 is tested and guaranteed to be with mouse species however ab57752 is only tested with human sampl...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - whole cell (HT-29)
Loading amount 10 µg
Specification HT-29
Treatment IP
Gel Running Conditions Reduced Denaturing (12)
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 27°C
Username

Ms. qianxue wan

Verified customer

提交于 Oct 10 2012

Thank you for your enquiry.
You are correct that both ab108599 and ab57752 are both monoclonal antibodies designed to detect tff3. In additiona they have both been found to detect human tff3 via WB and IHC-P. Other than these characteristics, thar...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"