Anti-Treacher Collins syndrome protein抗体(ab57683)

概述

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab57683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May be involved in nucleolar-cytoplasmic transport. May play a fundamental role in early embryonic development, particularly in development of the craniofacial complex.
    • 疾病相关Defects in TCOF1 are the cause of Treacher Collins syndrome type 1 (TCS1) [MIM:154500]. It is a form of Treacher Collins syndrome, a disorder of craniofacial development. Treacher Collins syndrome is characterized by a combination of bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids with a paucity of eyelashes medial to the defect, hypoplasia of the facial bones, cleft palate, malformation of the external ears, atresia of the external auditory canals, and bilateral conductive hearing loss.
    • 序列相似性Contains 1 LisH domain.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus > nucleolus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Mandibulofacial dysostosis antibody
      • MFD1 antibody
      • Nucleolar trafficking phosphoprotein antibody
      • TCOF 1 antibody
      • TCOF_HUMAN antibody
      • TCOF1 antibody
      • TCS antibody
      • TCS1 antibody
      • Treacher Collins Franceschetti syndrome 1 antibody
      • Treacher Collins syndrome antibody
      • Treacher Collins syndrome protein antibody
      • Treacle antibody
      • Treacle protein antibody
      see all

    Anti-Treacher Collins syndrome protein antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57683 Treacher Collins syndrome protein antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    Anti-Treacher Collins syndrome protein antibody (ab57683)参考文献

    ab57683 has not yet been referenced specifically in any publications.

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