Anti-Transglutaminase 6抗体(ab105725)

概述

  • 产品名称
    Anti-Transglutaminase 6抗体
    参阅全部 Transglutaminase 6 一抗
  • 描述
    兔多克隆抗体to Transglutaminase 6
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 418-467 (KKIGRCISTK AVGSDSRVDI TDLYKYPEGS RKERQVYSKA VNRLFGVEAS) of Human Transglutaminase 6 (CAI22900; UniProt ID O95932 isoform 2).

  • 阳性对照
    • NTERA2 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab105725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 µg/ml. TGM6 has two isoforms- 71 and 79kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
  • 疾病相关
    Defects in TGM6 are the cause of spinocerebellar ataxia type 35 (SCA35) [MIM:613908]. A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA35 patients commonly show upper limb involvement and torticollis. There is no cognitive impairment.
  • 序列相似性
    Belongs to the transglutaminase superfamily. Transglutaminase family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Protein-glutamine gamma-glutamyltransferase 6 antibody
    • TG6 antibody
    • TGase Y antibody
    • TGase-3-like antibody
    • TGase-6 antibody
    • TGM3L_HUMAN antibody
    • TGM6 antibody
    • TGY antibody
    • Transglutaminase Y antibody
    • Transglutaminase-3-like antibody
    • Transglutaminase-6 antibody
    see all

图片

  • Anti-Transglutaminase 6 antibody (ab105725) at 0.5 µg/ml + NTERA2 cell lysate at 10 µg

实验方案

文献

ab105725 has not yet been referenced specifically in any publications.

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