Anti-Transcription termination factor 1抗体(ab87726)

概述

  • 产品名称Anti-Transcription termination factor 1抗体
    参阅全部 Transcription termination factor 1 一抗
  • 描述
    兔多克隆抗体to Transcription termination factor 1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee
  • 免疫原

    Synthetic peptide, corresponding to a region within N terminal amino acids 1-50 of Human Transcription termination factor 1 (CAA58807.1)

  • 阳性对照
    • HeLa or 293T cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab87726 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/10000. Predicted molecular weight: 103 kDa.

靶标

  • 功能Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
  • 序列相似性Contains 2 Myb-like domains.
  • 结构域The N-terminal region (NRD) inhibits DNA-binding via its interaction with the C-terminal region.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus. Nucleus > nucleolus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • RNA polymerase I termination factor antibody
    • Transcription termination factor 1 antibody
    • Transcription termination factor I antibody
    • Transcription termination factor RNA polymerase I antibody
    • TTF 1 antibody
    • TTF-1 antibody
    • TTF-I antibody
    • Ttf1 antibody
    • TTF1_HUMAN antibody
    see all

Anti-Transcription termination factor 1 antibody 图像

  • All lanes : Anti-Transcription termination factor 1 antibody (ab87726) at 0.04 µg/ml

    Lane 1 : Whole cell lysate from HeLa cells at 50 µg
    Lane 2 : Whole cell lysate from HeLa cells at 15 µg
    Lane 3 : Whole cell lysate from HeLa cells at 5 µg
    Lane 4 : Whole cell lysate from 293T cells at 50 µg

    Developed using the ECL technique

    Predicted band size : 103 kDa
    Observed band size : ~118 kDa (why is the actual band size different from the predicted?)


    Exposure time : 30 seconds

Anti-Transcription termination factor 1 antibody (ab87726)参考文献

ab87726 has not yet been referenced specifically in any publications.

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