概述

  • 产品名称Anti-TRAIL抗体[N2B2] (Biotin)
    参阅全部 TRAIL 一抗
  • 描述
    大鼠单克隆抗体[N2B2] to TRAIL (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse TRAIL-transfected 2PK-3 cells.

  • 阳性对照
    • Mouse TRAIL transfected cells
  • 常规说明


    ab95531 inhibits IL2- or IL15-activated NK cell cytotoxicity against Mouse fibrosarcoma L929 target cells.

性能

应用

Our Abpromise guarantee covers the use of ab95531 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.125-0.25µg for 105-8 cells. in a final volume of 100 µL.



ab18445-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
  • 组织特异性Widespread; most predominant in spleen, lung and prostate.
  • 序列相似性Belongs to the tumor necrosis factor family.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apo 2 ligand antibody
    • APO 2L antibody
    • Apo-2 ligand antibody
    • Apo-2L antibody
    • APO2L antibody
    • CD253 antibody
    • CD253 antigen antibody
    • Chemokine tumor necrosis factor ligand superfamily member 10 antibody
    • Protein TRAIL antibody
    • TL2 antibody
    • TNF Related Apoptosis Inducing Ligand antibody
    • TNF related apoptosis inducing ligand TRAIL antibody
    • TNF-related apoptosis-inducing ligand antibody
    • TNF10_HUMAN antibody
    • TNFSF10 antibody
    • TRAIL antibody
    • Tumor necrosis factor (ligand) family member 10 antibody
    • Tumor Necrosis Factor (ligand) Superfamily Member 10 antibody
    • Tumor necrosis factor apoptosis inducing ligand splice variant delta antibody
    • Tumor necrosis factor ligand superfamily member 10 antibody
    see all

Anti-TRAIL antibody [N2B2] (Biotin) 图像

  • ab95531, at 0.125 µg, staining of TRAIL transfected cells (filled) or with Rat IgG2a Isotype Control (open) followed by Streptavidin PE by Flow Cytometry. Total viable cells were used for analysis.

Anti-TRAIL antibody [N2B2] (Biotin) (ab95531)参考文献

This product has been referenced in:
  • Hayakawa Y  et al. NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy. J Immunol 172:123-9 (2004). Read more (PubMed: 14688317) »
  • Kayagaki N  et al. Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells. J Immunol 163:1906-13 (1999). Flow Cyt ; Mouse . Read more (PubMed: 10438925) »

See all 2 Publications for this product

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