Anti-TRAIL抗体(ab231265)
Key features and details
- Rabbit polyclonal to TRAIL
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human, Recombinant fragment
- Isotype: IgG
概述
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产品名称
Anti-TRAIL抗体
参阅全部 TRAIL 一抗 -
描述
兔多克隆抗体to TRAIL -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse, Human, Recombinant fragment -
免疫原
Recombinant fragment corresponding to Mouse TRAIL aa 1 to the C-terminus. Two N-terminal tags, His-tag and S-tag. Expressed in E. coli.
Database link: P50592 -
阳性对照
- WB: A549 and MCF cell lysate. Recombinant mouse TRAIL protein. IHC-P: Kidney tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS -
Concentration information loading...
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纯度
Protein A purified -
纯化说明
Antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab231265于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use a concentration of 5 - 20 µg/ml.
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WB |
Use a concentration of 0.2 - 2 µg/ml.
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说明 |
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IHC-P
Use a concentration of 5 - 20 µg/ml. |
WB
Use a concentration of 0.2 - 2 µg/ml. |
靶标
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功能
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. -
组织特异性
Widespread; most predominant in spleen, lung and prostate. -
序列相似性
Belongs to the tumor necrosis factor family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 8743 Human
- Entrez Gene: 22035 Mouse
- Omim: 603598 Human
- SwissProt: P50591 Human
- SwissProt: P50592 Mouse
- Unigene: 478275 Human
- Unigene: 1062 Mouse
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别名
- Apo 2 ligand antibody
- APO 2L antibody
- Apo-2 ligand antibody
see all
图片
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Formalin-fixed, paraffin-embedded mouse kidney tissue stained for TRAIL with ab231265 at 20 µg/ml in immunohistochemical analysis. DAB staining.
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Anti-TRAIL antibody (ab231265) at 2 µg/ml + A549 (Human lung carcinoma cell line) cell lysate
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Anti-TRAIL antibody (ab231265) at 2 µg/ml + MCF7 (Human breast adenocarcinoma cell line) cell lysate
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Anti-TRAIL antibody (ab231265) at 2 µg/ml + Recombinant mouse TRAIL protein
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab231265 被引用在 2 文献中.
- Madka V et al. Oral administration of TRAIL-inducing small molecule ONC201/TIC10 prevents intestinal polyposis in the Apcmin/+ mouse model. Am J Cancer Res 12:2118-2131 (2022). PubMed: 35693092
- Zhang W et al. SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity. J Clin Invest 132:N/A (2022). PubMed: 36136587