概述

  • 产品名称Anti-TRAFD1抗体
    参阅全部 TRAFD1 一抗
  • 描述
    兔多克隆抗体to TRAFD1
  • 经测试应用适用于: IHC-P, ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Dog
  • 免疫原

    Synthetic peptide derived from a region between residues 395 - 444 of human TRAFD1.

    .

  • 阳性对照
    • Raji cell lysate for Western blot, and Epithelial cells of human renal tubule for Immunohistochemisty.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None.
    Constituents: 2% Sucrose, PBS.
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab25942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
ELISA 1/62500.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 63 kDa (predicted molecular weight: 65 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
  • 序列相似性Contains 1 TRAF-type zinc finger.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLN29 antibody
    • FLN29 gene product antibody
    • Protein FLN29 antibody
    • TRAD1_HUMAN antibody
    • TRAF type zinc finger domain containing 1 antibody
    • TRAF type zinc finger domain containing protein 1 antibody
    • TRAF-type zinc finger domain-containing protein 1 antibody
    • TRAFD 1 antibody
    • TRAFD1 antibody
    see all

Anti-TRAFD1 antibody 图像

  • Anti-TRAFD1 antibody (ab25942) at 1 µg/ml + Raji cell lysate.

    Predicted band size : 65 kDa
    Observed band size : 63 kDa (why is the actual band size different from the predicted?)
  • Ab25942 at a 4-8µg/ml dilution, staining epithelial cells of human kidney renal tubules by IHC-P. Magnification: X400.

Anti-TRAFD1 antibody (ab25942)参考文献

ab25942 has not yet been referenced specifically in any publications.

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