概述

  • 产品名称Anti-TRAF7抗体
    参阅全部 TRAF7 一抗
  • 描述
    兔多克隆抗体to TRAF7
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (GPAFSAVTTI TKADGTSTYK QHCRTPSSSS TLAYSPRDEE DSMPPISTPR) of Human TRAF7 (NP_115647).

  • 阳性对照
    • Human fetal stomach lysate

性能

应用

Our Abpromise guarantee covers the use of ab99022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 75 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed.
  • 组织特异性Ubiquitously expressed with high levels in skeletal muscle, heart, colon, spleen, kidney, liver and placenta.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the WD repeat TRAF7 family.
    Contains 1 RING-type zinc finger.
    Contains 1 TRAF-type zinc finger.
    Contains 7 WD repeats.
  • 翻译后修饰Phosphorylated by MAP3K3.
    Ubiquitinates itself upon phosphorylation.
  • 细胞定位Cytoplasmic vesicle. Colocalizes with MAP3K3 to vesicle-like structures throughout the cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • E3 ubiquitin protein ligase TRAF7 antibody
    • E3 ubiquitin-protein ligase TRAF7 antibody
    • RFWD1 antibody
    • Ring finger and WD repeat domain 1 antibody
    • RING finger and WD repeat-containing protein 1 antibody
    • RING finger protein 119 antibody
    • RNF119 antibody
    • TNF receptor associated factor 7 antibody
    • TNF receptor-associated factor 7 antibody
    • TRAF7 antibody
    • TRAF7_HUMAN antibody
    see all

Anti-TRAF7 antibody 图像

  • Anti-TRAF7 antibody (ab99022) at 1 µg/ml + Human fetal stomach lysate at 10 µg

    Predicted band size : 75 kDa

Anti-TRAF7 antibody (ab99022)参考文献

ab99022 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab99022.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"