概述

  • 产品名称Anti-TRAF5抗体
    参阅全部 TRAF5 一抗
  • 描述
    兔多克隆抗体to TRAF5
  • 经测试应用适用于: WB, IHC-P, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Human, Gerbil
  • 免疫原

    Synthetic peptide:

    MAHSEEQAAVPCAFIRQNSG

    , corresponding to N terminal amino acids 1-20 of Mouse TRAF5

  • 阳性对照
    • Spleen, lymphoid, many cancer cell lines.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: Whole serum
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab47539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/2000. Detects a band of approximately 65 kDa (predicted molecular weight: 64 kDa).
IHC-P Use at an assay dependent concentration.
IP 1/50 - 1/200.

靶标

  • 功能Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis.
  • 组织特异性Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.
  • 序列相似性Belongs to the TNF receptor-associated factor family. A subfamily.
    Contains 1 MATH domain.
    Contains 1 RING-type zinc finger.
    Contains 2 TRAF-type zinc fingers.
  • 结构域The MATH/TRAF domain binds to receptor cytoplasmic domains.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC:39780 antibody
    • RING finger protein 84 antibody
    • RNF 84 antibody
    • RNF84 antibody
    • TNF receptor associated factor 5 antibody
    • TNF receptor-associated factor 5 antibody
    • TRAF 5 antibody
    • Traf5 antibody
    • TRAF5_HUMAN antibody
    see all

Anti-TRAF5 antibody 图像

  • All lanes : Anti-TRAF5 antibody (ab47539) at 1/2000 dilution

    Lane 1 : Normal human testis tissue
    Lane 2 : Normal human kidney tissue
    Lane 3 : Normal human pancreas tissue
    Lane 4 : Normal human liver tissue
    Lane 5 : Normal human prostate tissue
    Lane 6 : Normal human breast tissue
    Lane 7 : Normal human colon tissue
    Lane 8 : Normal human thymus tissue
    Lane 9 : Normal human lymph node tissue
    Lane 10 : Normal human spleen tissue
    Lane 11 : Normal human lung tissue
    Lane 12 : Normal human aorta tissue
    Lane 13 : Normal human epidermis tissue


    Predicted band size : 64 kDa
    Observed band size : 64 kDa
  • Formalin-fixed, paraffin-embedded mouse spleen stained for TRAF5 expression using ab47539 at 1:2000. Hematoxylin-eosin counterstain. A1 is a higher magnification of A.
  • Formalin-fixed, paraffin-embedded mouse tissue stained for TRAF5 expression using ab47539 at 1:2000. Hematoxylin-eosin counterstain.

    A, thymus.

    B, bone marrow.

Anti-TRAF5 antibody (ab47539)参考文献

ab47539 has not yet been referenced specifically in any publications.

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