概述

  • 产品名称
    Anti-TRAF5抗体[55A219]
    参阅全部 TRAF5 一抗
  • 描述
    小鼠单克隆抗体[55A219] to TRAF5
  • 特异性
    ab12123 reacts with human TRAF5.
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Fusion protein corresponding to amino acid residue(s) 77 to 186 of human TRAF5.

  • 阳性对照
    • HeLa whole-cell extract.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    Affinity purified.
  • 克隆
    单克隆
  • 克隆编号
    55A219
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab12123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 66 kDa (predicted molecular weight: 66.8 kDa).

靶标

  • 功能
    Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis.
  • 组织特异性
    Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.
  • 序列相似性
    Belongs to the TNF receptor-associated factor family. A subfamily.
    Contains 1 MATH domain.
    Contains 1 RING-type zinc finger.
    Contains 2 TRAF-type zinc fingers.
  • 结构域
    The MATH/TRAF domain binds to receptor cytoplasmic domains.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC:39780 antibody
    • RING finger protein 84 antibody
    • RNF 84 antibody
    • RNF84 antibody
    • TNF receptor associated factor 5 antibody
    • TNF receptor-associated factor 5 antibody
    • TRAF 5 antibody
    • Traf5 antibody
    • TRAF5_HUMAN antibody
    see all

图片



  • Predicted band size : 66.8 kDa


    TRAF5 detection by Western blot. The analysis of 10 µg of HeLa cell extract by using ab12123 at a 2 µg/ml dilution.

实验方案

文献

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