概述

  • 产品名称
    Anti-TRADD抗体[EPR3604]
    参阅全部 TRADD 一抗
  • 描述
    兔单克隆抗体[EPR3604] to TRADD
  • 经测试应用
    适用于: WB, IP, IHC-P, ICCmore details
    不适用于: Flow Cyt
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to region within Human TRADD.

  • 阳性对照
    • Jurkat, MCF7, HeLa and K562 cell lysates Human breast carcinoma tissue HeLa cells
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

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应用

Our Abpromise guarantee covers the use of ab110644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 34 kDa (predicted molecular weight: 34 kDa).
IP 1/10.
IHC-P 1/100. Perform antigen retrieval before commencing with IHC staining protocol.
ICC 1/100.
  • 应用说明
    Is unsuitable for Flow Cyt.
  • 靶标

    • 功能
      Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
    • 组织特异性
      Found in all examined tissues.
    • 序列相似性
      Contains 1 death domain.
    • 结构域
      Requires the intact DEATH domain to associate with TNFRSF1A/TNFR1.
    • 细胞定位
      Cytoplasm > cytoskeleton.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 9130005N23Rik antibody
      • AA930854 antibody
      • TNFR1 associated DEATH domain protein antibody
      • TNFR1-associated DEATH domain protein antibody
      • TNFRSF1A associated via death domain antibody
      • TNFRSF1A-associated via death domain antibody
      • tradd antibody
      • TRADD_HUMAN antibody
      • Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody
      • Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody
      see all

    图片

    • All lanes : Anti-TRADD antibody [EPR3604] (ab110644) at 1/500 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : MCF7 cell lysate
      Lane 3 : HeLa cell lysate
      Lane 4 : K562 cell lysate

      Secondary
      Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution

      Predicted band size : 34 kDa
      Observed band size : 34 kDa
    • ab110644, at 1/100, staining TRADD in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry.
    • ab110644, at 1/100, staining TRADD in HeLa cells by Immunofluorescence.

    文献

    This product has been referenced in:

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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