概述

  • 产品名称Anti-TRADD抗体
    参阅全部 TRADD 一抗
  • 描述
    兔多克隆抗体to TRADD
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 1-13 of Human TRADD

  • 阳性对照
    • A549 and SiHa whole cell lysates A549 cells (IF)

性能

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应用

Our Abpromise guarantee covers the use of ab96552 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 34 kDa.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
  • 组织特异性Found in all examined tissues.
  • 序列相似性Contains 1 death domain.
  • 结构域Requires the intact DEATH domain to associate with TNFRSF1A/TNFR1.
  • 细胞定位Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 9130005N23Rik antibody
    • AA930854 antibody
    • TNFR1 associated DEATH domain protein antibody
    • TNFR1-associated DEATH domain protein antibody
    • TNFRSF1A associated via death domain antibody
    • TNFRSF1A-associated via death domain antibody
    • tradd antibody
    • TRADD_HUMAN antibody
    • Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody
    • Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody
    see all

Anti-TRADD antibody 图像

  • All lanes : Anti-TRADD antibody (ab96552) at 1/1000 dilution

    Lane 1 : A549 whole cell lysate
    Lane 2 : SiHa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 34 kDa
  • ab96552 at 1/200 dilution staining TRADD in paraformaldehyde-fixed A549 cells by immunofluorescence. The lower image shows ab96552 merged with a DNA probe.

Anti-TRADD antibody (ab96552)参考文献

ab96552 has not yet been referenced specifically in any publications.

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