概述

  • 产品名称Anti-TPM4抗体
    参阅全部 TPM4 一抗
  • 描述
    兔多克隆抗体to TPM4
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human TPM4 (N terminal).
    Database link: NM_003290

  • 阳性对照
    • Skeletal muscle

性能

应用

Our Abpromise guarantee covers the use of ab93645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/200 - 1/500.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
    • 组织特异性Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level).
    • 序列相似性Belongs to the tropomyosin family.
    • 结构域The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
    • 细胞定位Cytoplasm > cytoskeleton.
    • Information by UniProt
    • 数据库链接
    • 别名
      • epididymis secretory protein Li 108 antibody
      • HEL-S-108 antibody
      • TM30p1 antibody
      • TMP 4 antibody
      • TPM4 antibody
      • TPM4_HUMAN antibody
      • Tropomyosin 4 antibody
      • Tropomyosin alpha 4 chain antibody
      • Tropomyosin alpha-4 chain antibody
      • Tropomyosin-4 antibody
      • wu:fb06e07 antibody
      • zgc:103436 antibody
      • zgc:63909 antibody
      see all

    Anti-TPM4 antibody 图像

    • ab93645, at 1/100 dilution, showing cytoplasmic staining of TPM4 in formalin-fixed, paraffin-embedded skeletal muscle by Immunohistochemistry.

    Anti-TPM4 antibody (ab93645)参考文献

    ab93645 has not yet been referenced specifically in any publications.

    Product Wall

    Abreviews
    Abcam has not validated the combination of species/application used in this Abreview.
    Application Western blot
    Sample Human Cell lysate - whole cell (Rh30)
    Loading amount 20 µg
    Specification Rh30
    Gel Running Conditions Non-reduced Denaturing (NuPAGE 4-12% Bis-Tris Gel)
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: rt°C
    Username

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    提交于 Mar 14 2013

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"