概述

  • 产品名称Anti-TPM4抗体
    参阅全部 TPM4 一抗
  • 描述
    小鼠单克隆抗体to TPM4
  • 经测试应用适用于: WB, ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-249 of Human TPM4

性能

应用

Our Abpromise guarantee covers the use of ab58332 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ICC/IF
IHC-P
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IF/ICC: Use at a concentration of 10 µg/ml.
    IHC-P: Use at a concentration of 2 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
    • 组织特异性Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level).
    • 序列相似性Belongs to the tropomyosin family.
    • 结构域The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
    • 细胞定位Cytoplasm > cytoskeleton.
    • Information by UniProt
    • 数据库链接
    • 别名
      • epididymis secretory protein Li 108 antibody
      • HEL-S-108 antibody
      • TM30p1 antibody
      • TMP 4 antibody
      • TPM4 antibody
      • TPM4_HUMAN antibody
      • Tropomyosin 4 antibody
      • Tropomyosin alpha 4 chain antibody
      • Tropomyosin alpha-4 chain antibody
      • Tropomyosin-4 antibody
      • wu:fb06e07 antibody
      • zgc:103436 antibody
      • zgc:63909 antibody
      see all

    Anti-TPM4 antibody 图像

    • TPM4 antibody (ab58332) used in immunofluorescence at 10ug/ml on HeLa cells.
    • TPM4 antibody (ab58332) used in immunohistochemistry at 2ug/ml on formalin fixed and paraffin embedded human transitional cell carcinoma tissue.


    • Predicted band size : 28 kDa
      TPM4 antibody (ab58332) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-TPM4 antibody (ab58332)参考文献

    ab58332 has not yet been referenced specifically in any publications.

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