Anti-Tpit抗体(ab23475)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to Tpit
  • 特异性
    ab23475 reacts with T-box transcription factor (TBX19).
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Chicken, Cow, Dog, Chimpanzee, Zebrafish
  • 免疫原

    A region within synthetic peptide: AMSELGTRKP SDGTVSHLLN VVESELQAGR EKGDPTEKQL QIILEDAPLW, corresponding to N terminal amino acids 2-51 of Human Tpit

  • 阳性对照
    • WB: Jurkat cell lysate IHC-P: human kidney and human liver sections.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab23475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 1.5 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性
    Tpit (TBX19, T box 19) is a highly cell-restricted transcription factor belonging to the T-Box family. T box 19 is required for pro-opeiomelanocortin (POMC) gene expression and differentiation of corticotroph and melanotroph cells. Tpit gene mutations have been shown to be directly correlated to pituitary adrenocorticotropin (ACTH) deficiencies. Tpit functions as a transcriptional activator by recruiting the p160 family of coactivators.
  • 细胞定位
    Nuclear
  • 数据库链接
  • 别名
    • DJ747L4.1 antibody
    • T Box 19 antibody
    • T box factor, pituitary antibody
    • T box protein 19 antibody
    • T box transcription factor TBX19 antibody
    • TBS 19 antibody
    • TBS19 antibody
    • TBX19 antibody
    • TPIT antibody
    see all

Anti-Tpit antibody 图像

  • Anti-Tpit antibody (ab23475) at 2 µg/ml (Jurkat cell lysate)

    Performed under reducing conditions.

    Predicted band size : 48 kDa
    Observed band size : 48 kDa

实验方案

Anti-Tpit antibody (ab23475)参考文献

ab23475 has not yet been referenced specifically in any publications.

Product Wall

Merci de votre intérêt pour ab23475.

Le marquage en IHC avec cet anticorps est en effet incorrect. Merci de nous avoir informés ce cette erreur.
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Thank you for contacting us for technical support for your customer, I'm sorry to hear he is experiencing problems with ab23475. This is the first complaint we have had with this antibody which gave us a single clear band around 50kDa in Jurkat lysate....

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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