Anti-Toxoplasma gondii抗体[TP3] (ab8313)

概述

  • 产品名称Anti-Toxoplasma gondii抗体[TP3]
    参阅全部 Toxoplasma gondii 一抗
  • 描述
    小鼠单克隆抗体[TP3] to弓形虫
  • 特异性This antibody reacts with p30 membrane protein in ELISA and immunoblotting
  • 经测试应用适用于: ELISA, ICC/IF, WBmore details
  • 免疫原

    Tachizoites lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液PBS with 0.1% sodium azide, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号TP3
  • 骨髓瘤Sp2/0
  • 同种型IgG2a
  • 轻链类型unknown
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab8313 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
WB Use at an assay dependent concentration.

靶标

  • 相关性Toxoplasma is a crescent shaped sporozoan that lives as an intracellular parasite in various tissues of many vertebrates and completes its life cycle in a single host. Its life cycle includes two phases called the intestinal (or enteroepithelial) and extraintestinal phases. The intestinal phase produces oocysts and occurs only in cats, wild as well as domesticated. The extraintestinal phase occurs in all infected animals including cats, and produces tachyzoites (actively proliferating trophozoites) and eventually, bradyzoites (slowly growing trophozoites) or zoitocysts. Infection due to Toxoplasma gondii occurs in pregnant women where a variable degree of immunosuppression may exist or in patients receiving immunosuppressive drug therapy. Toxoplasma infects tissue of the GI tract where an active infection is accompanied by fever and enlargement of the spleen. Symptoms of toxoplasmosis are generally mild but severe infection of lymph nodes may occur. Congenital toxoplasmosis, in which the maternal infection is transmitted during pregnancy, can produce blindness or mental retardation in the newborn.
  • 别名
    • T. gondii antibody

Anti-Toxoplasma gondii antibody [TP3] (ab8313)参考文献

This product has been referenced in:
  • Zheng B  et al. The virulence-related rhoptry protein 5 (ROP5) of Toxoplasma Gondii is a novel vaccine candidate against toxoplasmosis in mice. Vaccine 31:4578-84 (2013). Read more (PubMed: 23928460) »
  • Kravets E  et al. The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii. J Biol Chem 287:27452-66 (2012). ICC/IF . Read more (PubMed: 22730319) »

See all 3 Publications for this product

Product Wall

Thank you for your enquiry. To use this antibody in IF I would recommend starting at a dilution of 1:100 or 1:200. Your customer will have to optimize based upon their results. Also, I updated our online datasheet to include the concentration of the cu...

Read More

Thank you for your enquiry. The antibody TP3 reacts only with p30 band in Western Blotting. It has been tested with purified Toxoplasma antigen and tachyzoites lysate.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"