Anti-Tollip抗体(ab37155)
Key features and details
- Rabbit polyclonal to Tollip
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-Tollip抗体
参阅全部 Tollip 一抗 -
描述
兔多克隆抗体to Tollip -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
Synthetic peptide corresponding to 16 amino acids near to the C terminus of the human Tollip protein.
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阳性对照
- WB: Rat brain cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab37155于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 30 kDa).
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说明 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 30 kDa). |
靶标
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功能
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. -
序列相似性
Belongs to the tollip family.
Contains 1 C2 domain.
Contains 1 CUE domain. -
翻译后修饰
Phosphorylated by IRAK1 upon stimulation by IL-1 or microbial products. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 361677 Rat
- SwissProt: A2RUW1 Rat
- Unigene: 137040 Rat
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别名
- Adapter protein antibody
- FLJ33531 antibody
- IL 1RAcPIP antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab37155 被引用在 4 文献中.
- Huang L et al. Tollip promotes hepatocellular carcinoma progression via PI3K/AKT pathway. Open Med (Wars) 17:626-637 (2022). PubMed: 35434373
- Zhi H et al. Tollip Negatively Regulates Vascular Smooth Muscle Cell-Mediated Neointima Formation by Suppressing Akt-Dependent Signaling. J Am Heart Assoc 7:N/A (2018). PubMed: 29887521
- Iyer RP et al. Defining the sham environment for post-myocardial infarction studies in mice. Am J Physiol Heart Circ Physiol 311:H822-36 (2016). PubMed: 27521418
- Vartanian KB et al. LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury. J Neuroinflammation 8:140 (2011). WB . PubMed: 21999375