概述

  • 产品名称
    Anti-TNRC6B抗体
  • 描述
    兔多克隆抗体to TNRC6B
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 180-229 (LQSESGTAPV WSKSTPPAPD NGTSAWGEPN ESSPGWGEMD DTGASTTGWG) of human TNRC6B (NP_001020014).

  • 阳性对照
    • Human fetal muscle lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Purified by peptide affinity chromatography method.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 109 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性
    TNRC6B belongs to the GW182 family. It contains one RRM (RNA recognition motif) domain. TNRC6B plays a role in RNA mediated gene silencing by both micro RNAs (miRNAs) and short interfering RNAs (siRNAs). It is required for miRNA dependent translational repression and siRNA dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. There are three named isoforms.
  • 细胞定位
    Cytoplasm, P-body. Mammalian P-bodies are also known as GW bodies, GWBs.
  • 数据库链接
  • 别名
    • KIAA1093 antibody
    • TNRC 6B antibody
    • Trinucleotide repeat containing 6B antibody
    • Trinucleotide repeat containing gene 6B protein antibody

图片

  • Anti-TNRC6B antibody (ab84308) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 109 kDa
    Observed band size : 109 kDa

实验方案

文献

ab84308 has not yet been referenced specifically in any publications.

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