概述

  • 产品名称Anti-TNNI3K抗体
    参阅全部 TNNI3K 一抗
  • 描述
    兔多克隆抗体to TNNI3K
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide derived from an internal region of Human TNNI3K.

  • 阳性对照
    • Human lung carcinoma tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49.1% PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: PBS is without Mg2+ and Ca2+.
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab111140 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111140 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 93 kDa. PubMed: 24925317
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能May play a role in cardiac physiology.
  • 组织特异性Highly expressed in both adult and fetal heart.
  • 序列相似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 10 ANK repeats.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated.
  • 细胞定位Nucleus. Cytoplasm. Expressed at lower levels in the cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cardiac ankyrin repeat kinase antibody
    • cardiac muscle antibody
    • Cardiac troponin I-interacting kinase antibody
    • CARK antibody
    • CMD1FF antibody
    • CMD2A antibody
    • CMH7 antibody
    • cTnl antibody
    • MGC142099 antibody
    • MGC33828 antibody
    • RCM1 antibody
    • Serine/threonine protein kinase TNN13K antibody
    • Serine/threonine-protein kinase TNNI3K antibody
    • TNI3K_HUMAN antibody
    • TNNC1 antibody
    • TNNI3 interacting kinase antibody
    • TNNI3-interacting kinase antibody
    • Tnni3k antibody
    • Troponin 1 antibody
    see all

Anti-TNNI3K antibody 图像

  • ab111140, at a 1/50 dilution, staining TNNI3K in paraffin embedded Human lung carcinoma tissue by Immunohistochemistry. Image on the right was from tissue treated with the synthetic peptide.

Anti-TNNI3K antibody (ab111140)参考文献

This product has been referenced in:
  • Theis JL  et al. TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy. Hum Mol Genet N/A:N/A (2014). WB ; Mouse . Read more (PubMed: 24925317) »

See 1 Publication for this product

Product Wall

The amino acid range of this immunogen is aa 200-250 of human Serine/threonine-protein kinase TNNI3K with Uniprot accession number Q59H18 (http://www.uniprot.org/uniprot/Q59H18). This antibody binds to the ANK5 and ANK6 repeats of isoforms 1, 2, 3, and...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"