Anti-TNNI3K抗体(ab111140)
Key features and details
- Rabbit polyclonal to TNNI3K
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TNNI3K抗体
参阅全部 TNNI3K 一抗 -
描述
兔多克隆抗体to TNNI3K -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Rat -
免疫原
Synthetic peptide derived from an internal region of Human TNNI3K.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49.1% PBS, 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine)
PBS is without Mg2+ and Ca2+. -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab111140 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111140于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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IHC-P
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
May play a role in cardiac physiology. -
组织特异性
Highly expressed in both adult and fetal heart. -
序列相似性
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Contains 10 ANK repeats.
Contains 1 protein kinase domain. -
翻译后修饰
Autophosphorylated. -
细胞定位
Nucleus. Cytoplasm. Expressed at lower levels in the cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 100526835 Human
- Entrez Gene: 51086 Human
- Entrez Gene: 295531 Rat
- SwissProt: Q59H18 Human
- SwissProt: Q7TQP6 Rat
- Unigene: 729320 Human
- Unigene: 3434 Rat
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别名
- Cardiac ankyrin repeat kinase antibody
- cardiac muscle antibody
- Cardiac troponin I-interacting kinase antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab111140 被引用在 2 文献中.
- Patterson M et al. Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nat Genet 49:1346-1353 (2017). PubMed: 28783163
- Theis JL et al. TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy. Hum Mol Genet N/A:N/A (2014). WB ; Mouse . PubMed: 24925317