Anti-Tnk1抗体[3F11H6] (ab70402)

概述

  • 产品名称Anti-Tnk1抗体[3F11H6]
    参阅全部 Tnk1 一抗
  • 描述
    小鼠单克隆抗体[3F11H6] to Tnk1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Purified truncated recombinant human Tnk1 (aa451-560)-His expressed in E.coli strain BL21 (DE3)

  • 阳性对照
    • Truncated Tnk1-His recombinant protein.

性能

应用

Our Abpromise guarantee covers the use of ab70402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: 1/10000.
    WB: 1/500 - 1/2000. Detects a band of approximately 17 kDa (predicted molecular weight: 73 kDa). Note: ab70402 has only been tested against a truncated recombinant protein.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
    • 组织特异性Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain.
    • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family.
      Contains 1 protein kinase domain.
      Contains 1 SH3 domain.
    • 翻译后修饰Autophosphorylated on tyrosine residues.
    • 细胞定位Cytoplasm. Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD38 negative kinase 1 antibody
      • EC 2.7.10.2 antibody
      • Kinase of embryonic stem cells antibody
      • Kos 1 antibody
      • Kos1 antibody
      • MGC46193 antibody
      • Non receptor tyrosine protein kinase TNK 1 antibody
      • Non receptor tyrosine protein kinase TNK1 antibody
      • Non-receptor tyrosine-protein kinase TNK1 antibody
      • Tnk 1 antibody
      • Tnk1 antibody
      • TNK1_HUMAN antibody
      • Tyrosine kinase non receptor 1 antibody
      see all

    Anti-Tnk1 antibody [3F11H6] 图像

    • All lanes : Anti-Tnk1 antibody [3F11H6] (ab70402) at 1/500 dilution

      Lane 1 : Molecular weight markers
      Lane 2 : Truncated Tnk1-His recombinant protein


      Predicted band size : 73 kDa
      Observed band size : 17 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.

    Anti-Tnk1 antibody [3F11H6] (ab70402)参考文献

    ab70402 has not yet been referenced specifically in any publications.

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