Anti-TNFRSF19L抗体(ab96220)
Key features and details
- Rabbit polyclonal to TNFRSF19L
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-TNFRSF19L抗体
参阅全部 TNFRSF19L 一抗 -
描述
兔多克隆抗体to TNFRSF19L -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant fragment, corresponding to a region within amino acids 35-366 of Human TNFRSF19L (NP_116260)
-
阳性对照
- 293T, A431, H1299, HepG2, MOLT4 and Raji cell lysate. HeLaS3 whole cell lysate. U87 xenograft tissue.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96220于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 46 kDa.
|
|
IHC-P |
1/100 - 1/500.
|
说明 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 46 kDa. |
IHC-P
1/100 - 1/500. |
靶标
-
功能
Mediates activation of NF-kappa-B. May play a role in T-cell activation. -
组织特异性
Highest levels are in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in brain, kidney and pancreas. -
序列相似性
Belongs to the RELT family.
Contains 1 TNFR-Cys repeat. -
翻译后修饰
Phosphorylated in vitro by OXSR1. -
细胞定位
Cell membrane. Cytoplasm. - Information by UniProt
-
数据库链接
- Entrez Gene: 84957 Human
- Entrez Gene: 320100 Mouse
- Entrez Gene: 361615 Rat
- Omim: 611211 Human
- SwissProt: Q969Z4 Human
- SwissProt: Q8BX43 Mouse
- Unigene: 533720 Human
- Unigene: 40336 Mouse
-
别名
- Receptor expressed in lymphoid tissues antibody
- Relt antibody
- TNFRSF19L antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (3)
ab96220 被引用在 3 文献中.
- Huang K et al. Construction and validation of a glioblastoma prognostic model based on immune-related genes. Front Neurol 13:902402 (2022). PubMed: 35968275
- Yao W et al. RELT promotes the growth of esophageal squamous cell carcinoma by activating the NF-?B pathway. Cell Cycle 20:1231-1241 (2021). PubMed: 34121605
- Cusick JK et al. RELT stains prominently in B-cell lymphomas and binds the hematopoietic transcription factor MDFIC. Biochem Biophys Rep 24:100868 (2020). PubMed: 33367115