概述

  • 产品名称Anti-TNFAIP8抗体
    参阅全部 TNFAIP8 一抗
  • 描述
    兔多克隆抗体to TNFAIP8
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 50-78 of Human TNFAIP8 (NP_055165.2, NP_001071122.1).

  • 阳性对照
    • K562 cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab107684 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 23 kDa.

靶标

  • 功能Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
  • 组织特异性Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle.
  • 序列相似性Belongs to the TNFAIP8 family.
  • 发展阶段Expressed at high levels in the fetal liver, lung and kidney.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GG2 1 antibody
    • Head and neck tumor and metastasis-related protein antibody
    • MDC-3.13 antibody
    • NDED antibody
    • NF-kappa-B-inducible DED-containing protein antibody
    • SCC S2 antibody
    • SCC-S2 antibody
    • SCCS2 antibody
    • TFIP8_HUMAN antibody
    • TNF alpha-induced protein 8 antibody
    • TNF induced protein antibody
    • TNF-induced protein GG2-1 antibody
    • TNFAIP 8 antibody
    • TNFAIP8 antibody
    • Tumor necrosis factor alpha induced protein 8 antibody
    • Tumor necrosis factor alpha-induced protein 8 antibody
    see all

Anti-TNFAIP8 antibody 图像

  • Anti-TNFAIP8 antibody (ab107684) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 23 kDa

Anti-TNFAIP8 antibody (ab107684)参考文献

ab107684 has not yet been referenced specifically in any publications.

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