Anti-TNF beta抗体[EP1113Y] (ab52639)


  • 产品名称Anti-TNF beta抗体[EP1113Y]
    参阅全部 TNF beta 一抗
  • 描述
    兔单克隆抗体[EP1113Y] to TNF beta
  • 经测试应用适用于: WBmore details
    不适用于: IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to residues near the N term of TNF beta (Human)

  • 阳性对照
    • Recombinant TNF beta
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.


    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.



Our Abpromise guarantee covers the use of ab52639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/5000. Detects a band of approximately 18 kDa (predicted molecular weight: 22 kDa).
  • 应用说明Is unsuitable for IP.
  • 靶标

    • 功能Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
    • 疾病相关Genetic variations in LTA are a cause of susceptibility psoriatic arthritis (PSORAS) [MIM:607507]. PSORAS is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoidlike pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis).
    • 序列相似性Belongs to the tumor necrosis factor family.
    • 细胞定位Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.
    • Information by UniProt
    • 数据库链接
    • 别名
      • LTalpha antibody
      • DIF antibody
      • LT alpha antibody
      • LT antibody
      • LT-alpha antibody
      • Lta antibody
      • Lymphotoxin alpha (TNF superfamily, member 1) antibody
      • Lymphotoxin alpha antibody
      • Lymphotoxin-alpha antibody
      • TNF B antibody
      • TNF superfamily member 1 antibody
      • TNF, lymphocyte-derived antibody
      • TNF-beta antibody
      • TNFB antibody
      • TNFB_HUMAN antibody
      • TNFbeta antibody
      • TNFSF1 antibody
      • TNLG1E antibody
      • Tumor necrosis factor beta antibody
      • tumor necrosis factor ligand 1E antibody
      • Tumor necrosis factor ligand superfamily member 1 antibody
      see all

    Anti-TNF beta antibody [EP1113Y] 图像

    • Anti-TNF beta antibody [EP1113Y] (ab52639) at 1/5000 dilution + Recombinant TNF beta at 0.05 µg

      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 22 kDa
      Observed band size : 18 kDa (why is the actual band size different from the predicted?)

    Anti-TNF beta antibody [EP1113Y] (ab52639)参考文献

    ab52639 has not yet been referenced specifically in any publications.

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