Anti-TNF beta抗体[359-81-11] (Phycoerythrin) (ab93517)

概述

  • 产品名称Anti-TNF beta抗体[359-81-11] (Phycoerythrin)
    参阅全部 TNF beta 一抗
  • 描述
    小鼠单克隆抗体[359-81-11] to TNF beta (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant Human TNF beta protein expressed in E.coli.

  • 阳性对照
    • Th1 polarized Human peripheral blood cells

性能

应用

Our Abpromise guarantee covers the use of ab93517 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 0.125µg for 105-8 cells in a final volume of 100 µl.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
    • 疾病相关Genetic variations in LTA are a cause of susceptibility psoriatic arthritis (PSORAS) [MIM:607507]. PSORAS is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoidlike pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis).
    • 序列相似性Belongs to the tumor necrosis factor family.
    • 细胞定位Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.
    • Information by UniProt
    • 数据库链接
    • 别名
      • LTalpha antibody
      • DIF antibody
      • LT alpha antibody
      • LT antibody
      • LT-alpha antibody
      • Lta antibody
      • Lymphotoxin alpha (TNF superfamily, member 1) antibody
      • Lymphotoxin alpha antibody
      • Lymphotoxin-alpha antibody
      • TNF B antibody
      • TNF superfamily member 1 antibody
      • TNF, lymphocyte-derived antibody
      • TNF-beta antibody
      • TNFB antibody
      • TNFB_HUMAN antibody
      • TNFbeta antibody
      • TNFSF1 antibody
      • TNLG1E antibody
      • Tumor necrosis factor beta antibody
      • tumor necrosis factor ligand 1E antibody
      • Tumor necrosis factor ligand superfamily member 1 antibody
      see all

    Anti-TNF beta antibody [359-81-11] (Phycoerythrin) 图像

    • Staining of Th1 polarized human peripheral blood cells with FITC anti-human CD4, followed by fixation, permeabilization and intracellular staining with 0.125 µg of ab93517 (right) or Phycoerythrin Mouse IgG1, K Iso Control (left). Total viable cells were used for analysis.

    Anti-TNF beta antibody [359-81-11] (Phycoerythrin) (ab93517)参考文献

    ab93517 has not yet been referenced specifically in any publications.

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