概述

  • 产品名称
    Anti-TMPRSS5抗体
    参阅全部 TMPRSS5 一抗
  • 描述
    山羊多克隆抗体to TMPRSS5
  • 宿主
    Goat
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Human
  • 免疫原

    Synthetic peptide:

    LDWIHDTAQDSLL

    , corresponding to C terminal amino acids 445-457 of Human TMPRSS5

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • 常规说明
    Principal Names - TMPRSS5; transmembrane protease, serine 5 (spinesin); SPINESIN; spinesin. Official Gene Symbol - TMPRSS5. GenBank Accession Number – NP_110397. LocusLink ID - 80975

性能

应用

Our Abpromise guarantee covers the use of ab2245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 52 kDa.

Detects two bands of approximately 35 and 52 kDa in mouse brain lysate.

靶标

  • 功能
    May play a role in hearing.
  • 组织特异性
    Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.
  • 疾病相关
    Note=Defects in TMPRSS5 may be a cause of deafness.
  • 序列相似性
    Belongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
    Contains 1 SRCR domain.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
    • 别名
      • MGC141886 antibody
      • MGC148044 antibody
      • OTTHUMP00000238209 antibody
      • OTTHUMP00000238210 antibody
      • OTTHUMP00000238211 antibody
      • OTTHUMP00000238212 antibody
      • OTTHUMP00000238213 antibody
      • Spinesin antibody
      • TMPRSS 5 antibody
      • TMPRSS5 antibody
      • TMPS5_HUMAN antibody
      • Transmembrane protease serine 5 antibody
      • Transmembrane protease, serine 5 (spinesin) antibody
      • Transmembrane protease, serine 5 antibody
      see all

    图片

    • Western blot - Anti-TMPRSS5 antibody (ab2245)
      Western blot - Anti-TMPRSS5 antibody (ab2245)
      ab2245 staining (2µg/ml) of Mouse Brain lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. ab2245 staining (2µg/ml) of Mouse Brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
    • Western blot - Anti-TMPRSS5 antibody (ab2245)
      Western blot - Anti-TMPRSS5 antibody (ab2245)
      ab2245 staining (0.5µg/ml) of Human Brain (Cerebral Cortex) lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

    实验方案

    文献

    This product has been referenced in:

    See 1 Publication for this product

    发表研究结果有使用 ab2245？请让我们知道，以便我们可以引用本数据表中的参考文章。

    客户评价及客户问答

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    1 Review or Q&A

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    I have an inquiry about your prodcut, AB2245: Spinesin antibody. Our researcher found your data using this antibody for western blot analysis and wants to know whether this result is under nonreducing conditions or resucing conditions. Please let...

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    Thank you for your enquiry and your patience, the source of ab2245 has confirmed that Western blots were done using reducing conditions. The exact protocol is below: - SDS PAGE. Samples were run at 200V constant on a 12% acrylamide SDS-PAGE min...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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